AED Neuroimaging SIG
Images and Papers
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McCormick et al., 2008
- Starved Brain
- Healthy Brain
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comments
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I have attached one of my articles that shows a 15% decrease in right dorsal ACC volume with starvation, which was correlated to reduced PIQ often seen in patients with AN. The degree to which the right dorsal ACC volume reverted back to normal was related to outcome as well. I have also attached an actual MRIs from an AN patient in one of my studies that demonstrates global brain atrophy before and restoration after weight gain.
Laurie McCormick, MD
Assistant Professor
University of Iowa Carver College of Medicine
Department of Psychiatry, Psychiatric Iowa Neuroimaging Consortium
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Bohon, C. & Feusner, J., unpublished data
- Underweight AN Brain
- Healthy Weight Brain
comments
Attached are two png files of a couple of brains from our study. One is from an underweight AN patient. She has not yet recovered, though, so we do not have a weight-restored scan for her. It is probably the best one we have, though, to really get a visual sense of atrophy. Our other pre- post- scans are much more subtle and would really require volumetrics to get a sense of the change rather than just a visual glance. The second scan I included is one of our control subjects as a comparison. Obviously, it's a different brain, so getting the slices to match isn't perfect, but you can at least get a comparison of underweight brain vs.normal weight brain - even if it's a different person.
Cara Bohon, Ph.D.
Postdoctoral Scholar-Fellow
University of California, Los Angeles
Department of Psychiatry and Biobehavioral Sciences
